MCH Alert: Focus on Infant Mortality


Maternal and Child Health Library

MCH Alert: Focus on Infant Mortality is developed by the Maternal and Child Health Library in collaboration with the National Sudden and Unexpected Infant/Child and Pregnancy Loss Resource Center at Georgetown University. This and past issues are available online at http://www.mchlibrary.info/alert/archives.html and http://www.sidscenter.org/alert/archives.html.


September 25, 2009

1. Program Support and Training Resource Posted Online
2. Brief Features Resources on Alcohol Use in Pregnancy and Its Impact
3. Study Investigates Heterogeneity of Preterm Birth Subtypes in Neonatal Death Risk
4. Article Analyzes Infant Sleep Positions Depicted in Magazines
5. Analyses Examine Racial Disparities in Stillbirth Risk Across Gestation

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1. PROGRAM SUPPORT AND TRAINING RESOURCE POSTED ONLINE

Helping Babies, Healing Families: A Program Manual and Trainer's Guide for Sudden and Unexpected Infant/Child Death and Pregnancy Loss supports state and local program staff in providing comprehensive risk reduction and bereavement services to families and their extended support networks, including health professionals. The online resource was adapted from a 2006 print document developed by the National Sudden and Unexpected Infant/Child Death and Pregnancy Loss Program Support Center and funded by the Maternal and Child Health Bureau (MCHB). Topics include what is sudden infant death syndrome, risk-reduction education, bereavement-support services, training, program expansion, research and statistics, partnerships and collaborations, public relations and the media, and fundraising and development. Information on how to conduct trainings, presentations, and informational sessions with public health nurses, first responders, child care providers, community groups, and others is included. The resource is available at http://www.programmanual.info

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2. BRIEF FEATURES RESOURCES ON ALCOHOL USE IN PREGNANCY AND IT'S IMPACT

Fetal Alcohol Spectrum Disorders (FASDs): Resource Brief compiles information sources on a group of conditions that can occur in a person whose mother drank alcohol during pregnancy. The brief, produced by the Maternal and Child Health (MCH) Library at Georgetown University, lists Web sites and related MCH Library resources. Sample resources include fact sheets and brochures; screening, diagnosis, surveillance, intervention, and training tools; and prevention-education materials (including materials in non-English languages). Additional resources include news, data and statistics, research findings, answers to frequently asked questions, and public service announcements. Electronic newsletters, toll-free information lines, and resource directories are also featured. The brief is available at http://mchlibrary.info/guides/fasd.html

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3. STUDY INVESTIGATES HETEROGENEITY OF PRETERM BIRTH SUBTYPES IN NEONATAL DEATH RISK

"The results generally suggest that heterogeneity of preterm birth subtypes on neonatal death risk exist," state the authors of an article published in the September 2009 issue of Obstetrics and Gynecology. Preterm birth can be classified into three clinical subtypes: spontaneous preterm labor with intact fetal membranes, preterm premature rupture of membranes (PROM) before onset of labor, and indicated preterm birth. Understanding the heterogeneity (dissimilarities) of preterm birth subtypes in relation to neonatal death can help describe the prognosis of preterm birth and provide related information for clinical decision-making. This study investigated the heterogeneity of preterm labor, preterm PROM, and indicated preterm birth in overall and gestational-age-specific neonatal death risk.

Data for the study were drawn from the National Center for Health Statistics' 2001 linked birth and infant death data sets (birth cohort, not period linked). The study sample was restricted to births and infant deaths in the 50 U.S. states and the District of Columbia area, excluding multiple births (because multiple births have much higher risk of preterm birth and infant death). Neonatal death was defined as neonates who died before 28 days of life, including early (0-6 days) and late (7-27 days) neonatal death. Because gestational age is an influential determinant of neonatal death, heterogeneity of preterm birth subtypes in relation to neonatal death can present in at least two ways: (1) distribution of gestational age and (2) gestational-age-specific neonatal death rate. Neonatal death risk was calculated as the number of neonatal deaths (neonates who died before 28 days) divided by the number of live births. Gestational-age-specific neonatal death risk was defined as the number of neonatal deaths in neonates born at a specific gestational age divided by the number of live births at that gestational age. The analyses compared the distribution of demographic and socioeconomic characteristics, birth outcomes, and neonatal death risk by preterm birth subtypes. The study also analyzed gestational-age-specific neonatal death risk by preterm-birth subtypes. Underlying causes of neonatal death were also explored to indicate possible heterogeneity.

The authors found that
The authors conclude, "Although gestational age is a strong predictor of neonatal death in preterm infants, preterm birth subtypes showed some heterogeneity in gestational age and birth weight distribution, risk of neonatal death, and the underlying causes of death."

Chen A, Feresu SA, Barsoom MJ. 2009. Heterogeneity of preterm birth subtypes in relation to neonatal death. Obstetrics and Gynecology 114(3):516-522. Abstract available at http://journals.lww.com/greenjournal/Abstract/2009/09000/Heterogeneity_of_Preterm_Birth_Subtypes_in.6.aspx

Readers: More information is available from the following MCH Library resource:

- Preconception and Pregnancy: Knowledge Path at
http://www.mchlibrary.info/KnowledgePaths/kp_pregnancy.html

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4. ARTICLE ANALYZES INFANT SLEEP POSITIONS DEPICTED IN MAGAZINES

"We found that messages communicated through photographs in magazine articles and advertisements often are inconsistent with public health messages about safe infant sleep environments," write the authors of an article published in the September 2009 issue of Pediatrics. Research has shown that messages in the media are influential in caregiver decisions about infant sleep position and that media messages are more likely to influence changes in infant sleep position than are health professional recommendations when initially released. In 2005, the American Academy of Pediatrics (AAP) published its most recent guidelines to reduce the risk of sudden infant death syndrome (SIDS), as follows: (1) place infants on the back for sleep, (2) avoid loose bedding, (3) avoid soft sleep surfaces, (4) avoid overheating, (5) consider a pacifier for sleep, (6) use room-sharing without bed-sharing, and (7) avoid prenatal and postnatal tobacco exposure. The aim of the study described in this article was to evaluate pictures in magazines that are widely read by women of childbearing age for adherence to AAP guidelines regarding safe infant sleep practices.

The authors obtained magazine readership data for fall 2007. Selection criteria for magazines to be included in this study were an average female readership of more than 5 million, circulation of more than 900,000, and a median age of female readers of 20 to 40. Twenty magazines met these criteria. An additional 8 magazines targeted toward expectant parents and parents of young children were included, for a total of 28 magazines. Pictures of infant sleep environments and sleeping infants that appeared in articles and advertisements in issues of these 28 magazines were analyzed for adherence to AAP guidelines for decreasing SIDS risk.

The authors found that
The authors conclude that "magazine publishers and advertisers must be made aware of the potential health impact of messages contrary to health care recommendations that are communicated through magazines."

Joyner BL, Gill-Bailey C, Moon RY. 2009. Infant sleep environments depicted in magazines targeted to women of childbearing age. Pediatrics 124(3):e416-e422. Available at http://www.pediatrics.org/cgi/content/full/124/3/e416

Readers: More information is available from National Sudden and Unexpected Infant/Child Death and Pregnancy Loss Resource Center at Georgetown University as follows:

- Safe Sleep at
http://sidscenter.org/SafeSleep/index.html

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5. ANALYSES EXAMINE RACIAL DISPARITIES IN STILLBIRTH RISK ACROSS GESTATION

This study reports "on factors contributing to racial disparities in the risk of stillbirth at different times in gestation," state the authors of an article published in the American Journal of Obstetrics and Gynecology (online ahead of print) on September 17, 2009. Risk factors may contribute differently to stillbirth hazard (stillbirth risk in ongoing pregnancies) depending on gestational age. The article presents findings from a study to examine the hazard of stillbirth by intervals of gestation in non-Hispanic whites, Hispanics, and non-Hispanic blacks and to determine the contribution of maternal and fetal characteristics to gestational age and racial differences in stillbirth hazard.

Data for the study were drawn from the National Center for Health Statistics' Perinatal Mortality Data Files and the Birth Cohort Linked Birth [and] Infant Death Data Sets for 2001-2002 combined. Stillbirth was defined as fetal death occurring at 20 or more weeks of gestation. The race-specific hazard of stillbirth and relative risk for non-Hispanic blacks vs. non-Hispanic whites at gestation intervals were stratified by maternal age, maternal education, and parity. The race-specific hazard of stillbirth for non-Hispanic blacks, non-Hispanic whites, and Hispanics at gestation intervals were also further calculated, excluding maternal medical conditions, pregnancy condition, labor condition, small-for-gestational-age deliveries, or deliveries with any reported congenital anomalies.

The authors found that
"This study demonstrates that preterm gestation is a period associated with increased vulnerability for stillbirth among black compared with white pregnancies," conclude the authors. More research is needed to understand the biologic threats to the fetus at preterm gestations, as well as the cultural and social determinants of racial disparities in risk among blacks and Hispanics.

Willinger M, Ko C-W, Reddy UM. 2009. Racial disparities in stillbirth risk across gestation in the United States. American Journal of Obstetrics and Gynecology [published online ahead of print on September 17, 2009]. Abstract available at http://www.ajog.org/article/S0002-9378(09)00701-7/abstract

Readers: More information is available from the following MCH Library resources:

- Infant Mortality and Pregnancy Loss: Knowledge Path at
http://mchlibrary.info/KnowledgePaths/kp_infmort.html

- Racial and Ethnic Disparities in Health: Knowledge Path at
http://mchlibrary.info/KnowledgePaths/kp_race.html

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MCH Alert © 1998-2009 by National Center for Education in Maternal and Child Health and Georgetown University. MCH Alert: Focus on Infant Mortality is produced by Maternal and Child Health Library at the National Center for Education in Maternal and Child Health at Georgetown University under its cooperative agreements (U02MC00001 and U48MC08717) with the Maternal and Child Health Bureau, Health Resources and Services Administration, U.S. Department of Health and Human Services. The Maternal and Child Health Bureau reserves a royalty-free, nonexclusive, and irrevocable right to use the work for federal purposes and to authorize others to use the work for federal purposes.
 
Permission is given to forward MCH Alert, in its entirety, to others. For all other uses, requests for permission to duplicate and use all or part of the information contained in this publication should be sent to mchalert@ncemch.org.

The editors welcome your submissions, suggestions, and questions. Please contact us at the address below.

MANAGING EDITOR: Jolene Bertness
CO-EDITOR: Tracy Lopez
COPYEDITOR/WRITER: Ruth Barzel
LIST ADMINISTRATOR: Beth DeFrancis Sun

MCH Alert
Maternal and Child Health Library
National Center for Education in Maternal and Child Health
Georgetown University
Box 571272
Washington, DC 20057-1272
Phone: (202) 784-9770
Fax: (202) 784-9777
E-mail: mchalert@ncemch.org
Web site: http://www.mchlibrary.info/alert


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