
Maternal and Child Health Library
MCH Alert: Focus on Infant Mortality is developed by the Maternal
and Child Health Library in collaboration with the National Sudden
and Unexpected Infant/Child and Pregnancy Loss Resource Center at
Georgetown University. This
and past issues are available online
at http://www.mchlibrary.info/alert/archives.html and http://www.sidscenter.org/alert/archives.html.
September 25, 2009
1. Program Support and Training Resource Posted Online
2. Brief Features Resources on Alcohol Use in Pregnancy
and Its Impact
3. Study Investigates Heterogeneity of Preterm Birth
Subtypes in Neonatal Death Risk
4. Article Analyzes Infant Sleep Positions Depicted in
Magazines
5. Analyses Examine Racial Disparities in Stillbirth Risk
Across Gestation
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1. PROGRAM SUPPORT AND TRAINING RESOURCE POSTED ONLINE
Helping Babies, Healing Families: A Program Manual and Trainer's Guide
for Sudden and Unexpected Infant/Child Death and Pregnancy Loss
supports state and local program staff in providing comprehensive risk
reduction and bereavement services to families and their extended
support networks, including health professionals. The online resource
was adapted from a 2006 print document developed by the National Sudden
and Unexpected Infant/Child Death and Pregnancy Loss Program Support
Center and funded by the Maternal and Child Health Bureau (MCHB).
Topics include what is sudden infant death syndrome, risk-reduction
education, bereavement-support services, training, program expansion,
research and statistics, partnerships and collaborations, public
relations and the media, and fundraising and development. Information
on how to conduct trainings, presentations, and informational sessions
with public health nurses, first responders, child care providers,
community groups, and others is included. The resource is available at http://www.programmanual.info
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2. BRIEF FEATURES RESOURCES ON ALCOHOL USE IN PREGNANCY AND IT'S IMPACT
Fetal Alcohol Spectrum Disorders (FASDs): Resource Brief compiles
information sources on a group of conditions that can occur in a person
whose mother drank alcohol during pregnancy. The brief, produced by the
Maternal and Child Health (MCH) Library at Georgetown University, lists
Web sites and related MCH Library resources. Sample resources include
fact sheets and brochures; screening, diagnosis, surveillance,
intervention, and training tools; and prevention-education materials
(including materials in non-English languages). Additional resources
include news, data and statistics, research findings, answers to
frequently asked questions, and public service announcements.
Electronic newsletters, toll-free information lines, and resource
directories are also featured. The brief is available at http://mchlibrary.info/guides/fasd.html
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3. STUDY INVESTIGATES HETEROGENEITY OF PRETERM BIRTH SUBTYPES IN
NEONATAL DEATH RISK
"The results generally suggest that heterogeneity of preterm birth
subtypes on neonatal death risk exist," state the authors of an article
published in the September 2009 issue of Obstetrics and Gynecology.
Preterm birth can be classified into three clinical subtypes:
spontaneous preterm labor with intact fetal membranes, preterm
premature rupture of membranes (PROM) before onset of labor, and
indicated preterm birth. Understanding the heterogeneity
(dissimilarities) of preterm birth subtypes in relation to neonatal
death can help describe the prognosis of preterm birth and provide
related information for clinical decision-making. This study
investigated the heterogeneity of preterm labor, preterm PROM, and
indicated preterm birth in overall and gestational-age-specific
neonatal death risk.
Data for the study were drawn from the National Center for Health
Statistics' 2001 linked birth and infant death data sets (birth cohort,
not period linked). The study sample was restricted to births and
infant deaths in the 50 U.S. states and the District of Columbia area,
excluding multiple births (because multiple births have much higher
risk of preterm birth and infant death). Neonatal death was defined as
neonates who died before 28 days of life, including early (0-6 days)
and late (7-27 days) neonatal death. Because gestational age is an
influential determinant of neonatal death, heterogeneity of preterm
birth subtypes in relation to neonatal death can present in at least
two ways: (1) distribution of gestational age and (2)
gestational-age-specific neonatal death rate. Neonatal death risk was
calculated as the number of neonatal deaths (neonates who died before
28 days) divided by the number of live births. Gestational-age-specific
neonatal death risk was defined as the number of neonatal deaths in
neonates born at a specific gestational age divided by the number of
live births at that gestational age. The analyses compared the
distribution of demographic and socioeconomic characteristics, birth
outcomes, and neonatal death risk by preterm birth subtypes. The study
also analyzed gestational-age-specific neonatal death risk by
preterm-birth subtypes. Underlying causes of neonatal death were also
explored to indicate possible heterogeneity.
The authors found that
- The proportion of preterm birth was 10.3 percent (0.8 percent
preterm PROM, 3.7 percent indicated preterm birth, and 5.8 percent
preterm labor).
- The neonatal death risk was 2.7 percent for preterm PROM, 1.8
percent for indicated preterm birth, and 1.1 percent for preterm labor.
- The effects of preterm birth subtypes differed by gestational
age. Preterm PROM and indicated preterm birth had higher risk of
neonatal death than preterm labor after 28 weeks of gestation. The
increased risk was not limited to early neonatal death in the first 7
days.
- When causes of neonatal death were separated, preterm birth
subtypes had different associations with these causes. At 24-27 weeks,
indicated preterm births tended to have a higher risk of neonatal death
from respiratory distress syndrome and respiratory conditions and birth
defects. At 28-36 weeks, preterm PROM also had higher risk of neonatal
death from these two conditions. Indicated preterm birth had higher
risk of neonatal death from all causes at 32-36 weeks.
The authors conclude, "Although gestational age is a strong predictor
of neonatal death in preterm infants, preterm birth subtypes showed
some heterogeneity in gestational age and birth weight distribution,
risk of neonatal death, and the underlying causes of death."
Chen A, Feresu SA, Barsoom MJ. 2009. Heterogeneity of preterm birth
subtypes in relation to neonatal death. Obstetrics and Gynecology
114(3):516-522. Abstract available at http://journals.lww.com/greenjournal/Abstract/2009/09000/Heterogeneity_of_Preterm_Birth_Subtypes_in.6.aspx
Readers: More information is available from the following MCH Library
resource:
- Preconception and Pregnancy: Knowledge Path at
http://www.mchlibrary.info/KnowledgePaths/kp_pregnancy.html
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4. ARTICLE ANALYZES INFANT SLEEP POSITIONS DEPICTED IN MAGAZINES
"We found that messages communicated through photographs in magazine
articles and advertisements often are inconsistent with public health
messages about safe infant sleep environments," write the authors of an
article published in the September 2009 issue of Pediatrics. Research
has shown that messages in the media are influential in caregiver
decisions about infant sleep position and that media messages are more
likely to influence changes in infant sleep position than are health
professional recommendations when initially released. In 2005, the
American Academy of Pediatrics (AAP) published its most recent
guidelines to reduce the risk of sudden infant death syndrome (SIDS),
as follows: (1) place infants on the back for sleep, (2) avoid loose
bedding, (3) avoid soft sleep surfaces, (4) avoid overheating, (5)
consider a pacifier for sleep, (6) use room-sharing without bed-sharing,
and (7) avoid prenatal and postnatal tobacco exposure. The aim of the
study described in this article was to evaluate pictures in magazines
that are widely read by women of childbearing age for adherence to AAP
guidelines regarding safe infant sleep practices.
The authors obtained magazine readership data for fall 2007. Selection
criteria for magazines to be included in this study were an average
female readership of more than 5 million, circulation of more than
900,000, and a median age of female readers of 20 to 40. Twenty
magazines met these criteria. An additional 8 magazines targeted toward
expectant parents and parents of young children were included, for a
total of 28 magazines. Pictures of infant sleep environments and
sleeping infants that appeared in articles and advertisements in issues
of these 28 magazines were analyzed for adherence to AAP guidelines for
decreasing SIDS risk.
The authors found that
- A total of 526 pictures from 34 issues were included in the
analysis.
- Of the 122 pictures of sleeping infants, 33 portrayed infants
being held by an adult or in a sitting position in a car seat, carrier,
or swing. Of the infants not being held, 57 (64 percent) were in the
supine position, and 32 (36 percent) in the side or prone position. Ten
of the sleeping infants were swaddled.
- The location where an infant was sleeping was identifiable in 31
pictures. Sleeping infants were most likely to be in slings or
backpacks (9 pictures), adult beds (7 pictures), cribs (5 pictures),
sofas (4 pictures), or car seats, carriers, or swings (3 pictures).
- Infants were pictured sleeping with blankets (26 pictures),
pillows (10 pictures), stuffed toys (2 pictures), and wedges (1
picture), and on soft surfaces (15 pictures).
- Of the 99 pictures of sleep environments that did not have an
infant visible, only 36 (36.4 percent) portrayed a safe sleep
environment as recommended by AAP.
The authors conclude that "magazine publishers and advertisers must be
made aware of the potential health impact of messages contrary to
health care recommendations that are communicated through magazines."
Joyner BL, Gill-Bailey C, Moon RY. 2009. Infant sleep environments
depicted in magazines targeted to women of childbearing age. Pediatrics
124(3):e416-e422. Available at http://www.pediatrics.org/cgi/content/full/124/3/e416
Readers: More information is available from National Sudden and
Unexpected Infant/Child Death and Pregnancy Loss Resource Center at
Georgetown University as follows:
- Safe Sleep at
http://sidscenter.org/SafeSleep/index.html
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5. ANALYSES EXAMINE RACIAL DISPARITIES IN STILLBIRTH RISK ACROSS
GESTATION
This study reports "on factors contributing to racial disparities in
the risk of stillbirth at different times in gestation," state the
authors of an article published in the American Journal of Obstetrics
and Gynecology (online ahead of print) on September 17, 2009. Risk
factors may contribute differently to stillbirth hazard (stillbirth
risk in ongoing pregnancies) depending on gestational age. The article
presents findings from a study to examine the hazard of stillbirth by
intervals of gestation in non-Hispanic whites, Hispanics, and
non-Hispanic blacks and to determine the contribution of maternal and
fetal characteristics to gestational age and racial differences in
stillbirth hazard.
Data for the study were drawn from the National Center for Health
Statistics' Perinatal Mortality Data Files and the Birth Cohort Linked
Birth [and] Infant Death Data Sets for 2001-2002 combined. Stillbirth
was defined as fetal death occurring at 20 or more weeks of gestation.
The race-specific hazard of stillbirth and relative risk for
non-Hispanic blacks vs. non-Hispanic whites at gestation intervals were
stratified by maternal age, maternal education, and parity. The
race-specific hazard of stillbirth for non-Hispanic blacks,
non-Hispanic whites, and Hispanics at gestation intervals were also
further calculated, excluding maternal medical conditions, pregnancy
condition, labor condition, small-for-gestational-age deliveries, or
deliveries with any reported congenital anomalies.
The authors found that
- The stillbirth hazard was highest at 20-23 weeks and 39-41 weeks
of gestation.
- Increased hazard was observed at every gestation interval for
blacks compared with the other racial-ethnic groups. The black-white
disparity in cumulative hazard was highest at 20-23 weeks (relative
risk, 2.75) and declined with increasing gestation, reaching the lowest
value at 39-40 weeks (relative risk, 1.57), and then increasing
slightly at 41 weeks.
- The stillbirth hazard for white women with 12 years or more of
education was 30 percent lower than the hazard for white women with 12
years or less of education. The influence of higher educational level
on reducing cumulative hazard of stillbirth was much less for blacks
(relative risk, 0.91) and not significant for Hispanics.
- The greatest contribution of pregnancy conditions to stillbirth
hazard occurred at less than 27 weeks of gestation.
- The contribution of any maternal condition (reported medical,
pregnancy, and labor conditions combined) to stillbirth hazard was
19.56 percent for non-Hispanic whites, 19.28 percent for Hispanics, and
30.9 percent for blacks.
- The contribution of small for gestational age and congenital
anomalies to stillbirth hazard was greater for whites compared with
blacks at preterm gestations, especially between 20-27 weeks, but
similar at 37-41 weeks.
"This study demonstrates that preterm gestation is a period associated
with increased vulnerability for stillbirth among black compared with
white pregnancies," conclude the authors. More research is needed to
understand the biologic threats to the fetus at preterm gestations, as
well as the cultural and social determinants of racial disparities in
risk among blacks and Hispanics.
Willinger M, Ko C-W, Reddy UM. 2009. Racial disparities in stillbirth
risk across gestation in the United States. American Journal of
Obstetrics and Gynecology [published online ahead of print on September
17, 2009]. Abstract available at http://www.ajog.org/article/S0002-9378(09)00701-7/abstract
Readers: More information is available from the following MCH Library
resources:
- Infant Mortality and Pregnancy Loss: Knowledge Path at
http://mchlibrary.info/KnowledgePaths/kp_infmort.html
- Racial and Ethnic Disparities in Health: Knowledge Path at
http://mchlibrary.info/KnowledgePaths/kp_race.html
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MCH Alert © 1998-2009 by National Center for Education in Maternal
and
Child Health and Georgetown University. MCH Alert: Focus on Infant
Mortality is produced by
Maternal and Child Health Library at the National Center for Education
in Maternal and Child Health at Georgetown University under its
cooperative agreements
(U02MC00001 and U48MC08717) with the Maternal and Child Health Bureau,
Health
Resources and Services Administration, U.S. Department of Health and
Human Services. The Maternal and Child Health Bureau reserves a
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Permission is given to forward MCH Alert, in its entirety, to others.
For
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Please contact us at the address below.
MANAGING EDITOR: Jolene Bertness
CO-EDITOR: Tracy Lopez
COPYEDITOR/WRITER: Ruth Barzel
LIST ADMINISTRATOR: Beth DeFrancis Sun
MCH Alert
Maternal and Child Health Library
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Georgetown University
Box 571272
Washington, DC 20057-1272
Phone: (202) 784-9770
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E-mail: mchalert@ncemch.org
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